Our technology is supported by numerous scientific publications:
Our team has shown that selective small molecules can deplete albumin and top highly-abundant proteins in plasma, significantly improving the depth of plasma proteome profiling (Link to article).
We have refined various parameters in experimental design, sample preparation protocols, mass spectrometry analysis and database search to homogenize plasma proteome profiling across various cohorts (Link to article).
Our team consists of opinion leaders, shaping the future of protein corona analysis and its applications in biomarker discovery and other disciplines (Link to article)
We are also front-runners in applying the technology to characterization of intact proteoforms in protein corona, using top-down proteomics (Link to article).
Our recent efforts are aimed at integrating bottom-up and top-down proteomics for more comprehensive characterization of proteoforms and annotating the post-translational modifications, for next-generation biomarker discovery (Link to article).